Treatment of Lyme Disease with Lyme Carditis in Haemodynamically Stable Patients Aged 9 and Over
When Lyme disease is complicated by Lyme carditis and the patient remains haemodynamically stable, a specific antibiotic protocol applies. This page outlines the clinical scenario and treatment approach for patients aged 9 years and over.
Clinical Scenario
The patient has confirmed Lyme disease with concurrent Lyme carditis — cardiac involvement associated with Borrelia infection. Haemodynamic stability at presentation is a key determinant of the treatment pathway. This protocol is indicated for patients aged 9 years and over, with weight-based dosing considerations applying within the paediatric range.
References
DOI: 10.1093/cid/ciaa1215
- Lyme disease with Lyme carditis
- Lyme disease with Lyme carditis and haemodynamically stable
- For adults and young people (aged 12 and over) diagnosed with Lyme disease, offer antibiotic treatment according to their symptoms as described in table 1.
- Oral doxycycline: 100 mg twice per day or 200 mg once per day for 21 days
- Intravenous ceftriaxone: 2 g once per day for 21 days
- Oral doxycycline for children under 45 kg: 5 mg/kg in 2 divided doses on day 1 followed by 2.5 mg/kg daily in 1 or 2 divided doses for a total of 21 days
- Intravenous ceftriaxone for children under 50 kg: 80 mg/kg (up to 2 g) once per day for 21 days