Treatment of Lyme Disease with Arthritis or Acrodermatitis Chronica Atrophicans (Age 9 and Over)
This protocol covers antibiotic treatment for patients aged 9 years and over presenting with Lyme disease in the context of arthritis or acrodermatitis chronica atrophicans (ACA). Antibiotic selection is guided by the patient's presentation, age, and weight.
Clinical Scenario
Lyme disease with arthritis or acrodermatitis chronica atrophicans in patients aged 9 years and over. Both manifestations require directed antibiotic therapy, with regimen choice adapted to the individual patient.
Treatment Approach (Partial Overview)
The protocol involves oral antibiotic therapy as the primary approach, with an intravenous option available when oral treatment is contraindicated or unsuitable. Drug selection and specific parameters differ by patient age and weight class.
Full regimen details, weight-based dosing, and the complete decision pathway are available via the link below.
References
DOI: 10.1093/cid/ciaa1215
- Lyme disease with arthritis
- Lyme disease with acrodermatitis chronica atrophicans
- For adults and young people (aged 12 and over) diagnosed with Lyme disease, offer antibiotic treatment according to their symptoms as described in table 1.
- Oral doxycycline: 100 mg twice per day or 200 mg once per day for 28 days
- Oral amoxicillin: 1 g 3 times per day for 28 days
- Intravenous ceftriaxone: 2 g once per day for 28 days
- Oral doxycycline for children under 45 kg: 5 mg/kg in 2 divided doses on day 1 followed by 2.5 mg/kg daily in 1 or 2 divided doses for a total of 28 days
- Oral amoxicillin for children 33 kg and under: 30 mg/kg 3 times per day 28 days
- Intravenous ceftriaxone for children under 50 kg: 80 mg/kg (up to 2 g) once per day for 28 days
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