Treatment of Lyme Disease Affecting the Central Nervous System in Children Under 9 Years

When Lyme disease involves the central nervous system in a child under 9 years of age, antibiotic treatment must follow age-specific guidance. This protocol addresses that precise clinical scenario.

Clinical scenario: Lyme disease with central nervous system involvement; patient age under 9 years. For children diagnosed with Lyme disease, antibiotic treatment is selected and adjusted according to their specific symptoms, with distinct considerations applying to this younger age group.

Treatment approach

Management in this scenario involves intravenous ceftriaxone, with the dose and course determined by the child's weight. The complete weight-based dosing, daily quantity, and treatment duration are detailed in the full protocol.

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References

DOI: 10.1093/cid/ciaa1215
Lyme disease affecting the central nervous system
For children (under 12) diagnosed with Lyme disease, offer antibiotic treatment according to their symptoms as described in table 2.
Intravenous ceftriaxone for children under 50 kg: 80 mg/kg (up to 4 g) once per day for 21 days

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