Chronic Non-Specific Low Back Pain Persisting More Than 12 Weeks in Adults

Clinical Scenario

This protocol is for adults aged 18 and over with non-specific low back pain whose symptoms have persisted for more than 12 weeks. Clinical practice guidelines consistently define this 12-week threshold as the point at which the condition is classified as chronic, warranting a structured, multimodal management approach distinct from shorter-duration presentations.

Management Overview

Evidence-based management at this stage integrates physical and psychological components. Therapeutic exercise is a cornerstone of the approach, alongside cognitive behavioural therapy (CBT). The complete protocol — including the pharmacological options and the structured sequencing across all intervention types — is available in full below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1186/s12891-024-07468-0

CPGs focusing on information regarding the management and/or treatment of non-specific LBP were considered eligible.
The CPG concerned adult populations (18 years or over).
All guidelines defined chronic LBP as more than 12 weeks in duration.
They recommended therapeutic exercise (n = 13), CBT (n = 10), opioids (n = 6), antidepressants (n = 6), among other interventions.
Further recommendations about other drugs like paracetamol, opioids, muscle relaxants and antidepressants vary considerably.

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