Treatment of Liver Cirrhosis with Portal Hypertensive Gastropathy and Chronic Iron Deficiency Anaemia

In patients with liver cirrhosis, portal hypertensive gastropathy (PHG) can produce chronic haemorrhage that leads to chronic iron deficiency anaemia. This specific combination defines a recognised clinical scenario with a distinct first-line management approach.

Clinical scenario

Liver cirrhosis complicated by portal hypertensive gastropathy with chronic haemorrhage and resulting chronic iron deficient anaemia.

First-line approach — partial overview

Management centres on a non-selective beta-blocker to reduce portal pressure, combined with measures to address the iron deficiency. Blood support may also be incorporated when clinically indicated.

Complete regimen details, individualised decision criteria, and structured guidance are available in the full protocol.

Instant Access to Structured Evidence-Based Regimens

References

NSBB and iron supplementation and/or blood transfusion, when indicated, are recommended as first-line therapy for chronic haemorrhage from PHG is an (I;1).

DOI: 10.1016/j.jhep.2018.03.024

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