What Is the First-Line Treatment of Liver Cirrhosis?

Liver cirrhosis represents the end stage of chronic liver injury, in which ongoing damage drives progressive scarring and loss of normal hepatic function. First-line management prioritises eliminating the cause of that ongoing injury before further complications arise.

The primary strategy centres on removing the aetiological factor responsible for liver injury. This is particularly important when the cause is alcohol use or chronic viral hepatitis infection — interventions targeting these factors are associated with reduced risk of decompensation and improved survival. The full protocol details the specific clinical pathway for each aetiology, including criteria for initiating treatment.

Complete regimen — including treatment selection criteria — available in the structured protocol.