Treatment of Liver Cell Adenoma with Ten or More Hepatic Adenomas (Hepatic Adenomatosis)
Clinical Scenario
Hepatic adenomatosis is a recognised variant of hepatic cell adenoma (HCA) defined by the simultaneous presence of ten or more hepatic adenomas. This multifocal burden distinguishes it from solitary or oligofocal disease and carries distinct management considerations.
Condition Details
Hepatic adenomatosis is more commonly associated with background steatosis or glycogen storage disease. The designation of adenomatosis applies specifically when multifocal hepatic nodules number ten or more, representing a clinically significant threshold that guides therapeutic decision-making.
Treatment Approach (Overview)
For select patients carrying this degree of multifocal hepatic adenoma burden, a transplantation-based surgical strategy may be considered. The full eligibility criteria, decision algorithm, and protocol details are available in the complete regimen below.
References
- Hepatic adenomatosis is a variant of HCA characterized by 10 or more hepatic adenomas, more commonly associated with background steatosis or glycogen storage disease.
- The presence of multifocal (.10) nodules has been defined as adenomatosis.
- As explained below, liver transplantation is reserved for select patients with multiple HCAs.
DOI: 10.14309/ajg.0000000000002857
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