Treatment of Liver Cell Adenoma in Male Sex with Hepatic Adenoma

In male patients, a diagnosis of hepatic adenoma carries a higher incidence of malignancy than in other populations. This elevated risk applies regardless of lesion size or subtype, and it directly drives the recommended clinical management approach.

Clinical scenario: Male sex with confirmed hepatic adenoma. Men with hepatic adenomas should be considered for surgical resection regardless of lesion size because of elevated risk of malignant transformation.

Treatment approach

Management involves a definitive surgical intervention — with a specific operative approach strongly preferred — combined with guidance on modifiable contributing factors. The full structured protocol, including the complete decision criteria and sequence of interventions, is available via the link below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.14309/ajg.0000000000002857

For males, regardless of size or subtype, adenomas should be surgically resected or treated definitively because of the higher incidence of malignancy.

Men with hepatic adenomas should consider surgical resection regardless of lesion size because of elevated risk of malignant transformation.

Laparoscopic liver resection is strongly preferred over nonsurgical modalities.

They should also be encouraged to eliminate anabolic steroid or exogenous steroid use and recommended weight loss.

View source ↗