Treatment of Listeriosis in Pregnancy: Isolated Listerial Bacteraemia Without Meningitis
This protocol covers the management of a pregnant woman with isolated listerial bacteraemia, confirmed without meningitis or endocarditis, in a patient who is not allergic to penicillins.
Clinical Scenario
Pregnant patient presenting with isolated listerial bacteraemia. There is no meningitis and no endocarditis. The patient has no penicillin allergy. This specific combination of pregnancy and isolated bacteraemia determines the treatment pathway.
Treatment Approach
Treatment is based on ampicillin antibiotic therapy. The complete regimen — including dosing, administration, and duration — is detailed in the full structured protocol.
References
- Ampicillin alone can be used in pregnant women with isolated listerial bacteraemia.
- Bacteremic patients without CSF abnormalities can be treated for 2 weeks; meningitis should be treated for 3 weeks; relapses have been documented with shorter durations of therapy.