Treatment of Localised, Clinically Unresectable Liposarcoma of an Extremity or Superficial Trunk

Clinical Scenario

This protocol applies to patients with localised liposarcoma arising in an extremity or the superficial trunk that is clinically unresectable at the time of presentation. Primary unresectability — the inability to achieve adequate surgical removal at the outset — defines this sub-population and guides the clinical pathway.

Management Approach

The structured approach centres on surgical management as the primary modality, with the potential role of radiotherapy addressed as part of the overall plan. The complete protocol specifies the resectability criteria that determine timing and the conditions under which additional modalities apply.

Full sequencing, eligibility criteria, and all decision points are available in the complete protocol below.