Treatment of Digital Ulcers in Limited Cutaneous Systemic Sclerosis
Patients with limited cutaneous systemic sclerosis (lcSSc) can develop painful digital ulcers — a significant complication requiring targeted management. The clinical priorities are healing active ulcers and preventing the formation of new ones.
Healing of digital ulcers
Reduction in number of new digital ulcers
Treatment Approach (partial summary)
The protocol addresses active ulcer healing with vasodilatory therapy, and separately targets the prevention of new digital ulcers with a distinct agent.
Full regimen, sequencing, and prescribing details are in the complete protocol →
References
DOI: 10.1136/ard-2024-226430
- PDE5 inhibitors and/or intravenous iloprost should be considered for the treatment of digital ulcers in patients with SSc.
- Bosentan should be considered for reduction of number of new digital ulcers in SSc.
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