Laryngeal Cancer
ICD-10 C32 · ICD-11 2C23

Treatment of Laryngeal Cancer with Distant Recurrence

This protocol addresses laryngeal cancer that has recurred at a distant site — spread beyond the original tumour to other parts of the body, such as the lungs or bone. This presentation requires a systemic treatment strategy rather than local control alone.

When distant recurrence has occurred and radiation therapy or surgery are not viable options, immunotherapy — alone or in combination with chemotherapy — is a central approach. Additional systemic options, including targeted agents, may also be considered depending on the clinical picture.

Full regimen details, sequencing, and eligibility criteria are in the complete protocol below.
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References

  1. A distant recurrence, where radiation therapy and surgery are not options, can be treated with immunotherapy alone or immunotherapy combined with chemotherapy.
  2. Another option might be treatment with a targeted agent, either alone or with chemotherapy.
  3. Chemoradiation might also be used, if a person can physically tolerate it.
  4. If there are only a few tumors, surgery may be done.
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