Treatment of Laryngeal Cancer — Stage 0 (Carcinoma in Situ), Glottic

Stage 0 laryngeal cancer, or carcinoma in situ (CIS), represents the earliest form of laryngeal malignancy. This protocol addresses the specific clinical situation of stage 0 disease, which is almost always glottic — meaning it involves the vocal cords.

Clinical Scenario

These cancers are almost always glottic (vocal cord) cancers that are found early because of voice changes. The localised, pre-invasive nature of stage 0 disease defines both the management approach and the expectation of outcome.

Treatment Approach

Management of stage 0 glottic carcinoma in situ involves a localised intervention — either a surgical or a radiation-based approach. The full protocol specifies which option applies and under what clinical conditions.

Complete regimen details, including the recommended modality and clinical decision points, are available in the structured protocol below.