Treatment of Recurrent Herpes Labialis (Cold Sores)

Recurrent herpes labialis — cold sores — involves repeated episodes of perioral HSV-1 reactivation. Effective management hinges on recognising the pattern of recurrence and acting quickly when symptoms begin.

Clinical Scenario

Patients with recurrent herpes labialis experience repeated outbreaks of perioral blistering and ulceration. Initiating therapy at the very onset of symptoms or prodromal signs is a key feature of this management approach.

Treatment Approach (partial overview)

Management centres on episodic antiviral therapy started promptly at symptom onset. Oral antiviral agents represent the primary treatment class, with topical alternatives available but generally considered less effective … [full regimen and options in the protocol]

Treatment Goals

Healing of herpes labialis lesions and resolution of pain.

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References

Oral acyclovir, valacyclovir, and famciclovir are effective in treating acute recurrence of herpes labialis (cold sores).

Oral acyclovir, valacyclovir (Valtrex), and famciclovir (Famvir) are effective for the treatment of acute recurrences of herpes labialis.

Topical acyclovir, penciclovir (Denavir), and docosanol (Abreva) are optional treatments for recurrent herpes labialis, but they are less effective than oral treatment.

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