Treatment of Knee Osteoarthritis When Standard Analgesic Options Are Contraindicated, Not Tolerated, or Inadequate

Knee osteoarthritis is a common degenerative joint condition associated with chronic pain and functional limitation. While established first-line analgesic approaches apply to most patients, a subset experience contraindications, intolerance, or an inadequate response to standard therapy. This protocol addresses pain management specifically in that situation.

When standard options are not viable, the protocol includes an oral analgesic option considered appropriate for pain relief in the absence of alternatives.