Knee Osteoarthritis
ICD-10 M17 · ICD-11 FA01

Knee Osteoarthritis: First-Line Intra-articular Injection Approach

This protocol addresses knee osteoarthritis in patients for whom an intra-articular intervention is indicated as a first-line management strategy. Multiple major clinical guidelines converge on this approach for the affected knee joint.

Treatment Approach

The protocol centers on an intra-articular injection administered directly into the knee. This modality is broadly endorsed across guidelines, and the complete structured regimen — including clinical criteria, procedural considerations, and follow-up guidance — is available in the full protocol.

Dosing, frequency, and full algorithm are in the complete protocol.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1016/j.rdc.2022.03.009. In terms of intra-articular therapies, all of the guidelines recommended intra-articular corticosteroid (IACS) injections for the knee and hip, with most providing a weak or conditional recommendation and ACR/AF providing a strong recommendation. View source ↗