When a patient with keratosis pilaris has undergone advanced procedural interventions — including dermabrasion, photodynamic treatment, laser-based therapies, or blue light treatment — and those approaches have not achieved adequate reduction of redness, inflammation, or surface irregularity, escalation to a systemic treatment line is the next step in management.
The previous treatment line consisted of advanced procedural therapies: dermabrasion, photodynamic treatment, laser treatments (pulsed dye, fractional, or Nd laser), and blue light therapy. That line failed to reach its clinical goals of reduced redness and inflammation and smoother skin texture with less noticeable bumps. Failure to achieve those endpoints is the basis for moving to this protocol.