Treatment of Iron-Deficiency Anemia in Portal Hypertensive Gastropathy

This protocol applies to patients with iron-deficiency anemia occurring in the context of portal hypertensive gastropathy — a condition in which chronic mucosal bleeding can progressively deplete iron stores.

Portal hypertensive gastropathy creates an ongoing source of blood loss that directly contributes to iron-deficiency anemia. Initial management focuses on replenishing iron stores, but the presence of continued bleeding can affect how and when different therapeutic routes are considered.

The protocol includes an intravenous iron strategy for a specific subset of patients — those with ongoing bleeding who have not responded adequately to oral iron therapy. The complete regimen, clinical criteria, and sequencing go beyond what is shown here.

Full protocol details — including decision criteria, sequencing, and clinical thresholds — are available via the structured regimen below.