Treating Iron-Deficiency Anemia in Celiac Disease
Clinical Scenario
Celiac Disease
This protocol addresses iron-deficiency anemia occurring in the setting of celiac disease — a combination in which underlying intestinal pathology directly affects iron absorption and management decisions.
Key Consideration
In patients with both iron-deficiency anemia and celiac disease, the gastrointestinal context of celiac disease is central to the management approach. Restoring normal intestinal absorptive function is a core part of addressing the iron deficit.
Management Approach (Partial)
Management centres on dietary intervention to address the underlying absorptive impairment, with iron repletion considered according to the severity of the deficiency.
The complete sequenced regimen — including specific supplementation strategy and escalation pathway — is available in the full protocol below.
References
- In patients with iron-deficiency anemia and celiac disease, ensure adherence to a gluten-free diet to improve iron absorption.
- Consider oral iron supplementation based on the severity of iron deficiency and patient tolerance, followed by intravenous iron therapy if iron stores do not improve.
DOI: 10.1016/j.cgh.2024.03.046
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