Treatment of Intraductal Papilloma of Breast: Peripheral Presentation with Nipple Discharge or Breast Mass on Imaging

Clinical Scenario

This protocol addresses peripheral intraductal papilloma of the breast presenting with nipple discharge or a breast mass identified on imaging, in the absence of atypical ductal hyperplasia.

Presentation

Peripheral intraductal papilloma is typically concealed within the breast and comes to clinical attention through nipple discharge or a breast mass that can be detected by imaging examination. This pattern of presentation, without atypical ductal hyperplasia, defines the population for this management pathway.

Management Approach

Surgical intervention is among the options available for peripheral intraductal papilloma in this setting — but less invasive tissue-sampling procedures may also be considered depending on clinical factors. The structured protocol specifies the indications and sequencing for each approach.

Complete procedure selection criteria and clinical algorithm available via the full protocol.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1097/CM9.0000000000001533

Peripheral intraductal papilloma is usually concealed and is characterized by nipple discharge or a breast mass that can be found by imaging examination.

For central intraductal papilloma with nipple discharge, open surgery is recommended and should include lobular resection or quadrant resection including the intraductal lesion; open surgery or CNB/VABB can be performed for peripheral intraductal papilloma.

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