Hypophysitis can present acutely with rapidly developing neurological deficits arising from pituitary enlargement and mass compression of surrounding structures. This clinical pattern warrants prompt evaluation and a structured management approach tailored to the severity and pace of deterioration.
Rapid onset of neurological symptoms with mass effects due to pituitary enlargement — a time-sensitive presentation in which immunosuppressive therapy is among the recognized management strategies.
In carefully selected cases, a surgical intervention via the transsphenoidal route forms part of the evidence-based management pathway. The full indications, sequencing, and protocol details are available through the complete regimen.
DOI: 10.1016/j.beem.2019.101371
Immunosuppressive therapy is utilized for patients with rapid onset of neurological symptoms and mass effects due to pituitary enlargement.
Surgery should be reserved for cases of uncertain diagnosis, rapid progression of neurological symptoms, and large space-occupying lesions that are accessible through transsphenoidal approach.
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