Hypophysitis in Premenopausal Women with Central Hypogonadism

This protocol addresses hypophysitis in a premenopausal female patient where pituitary inflammation has led to central hypogonadism — impaired gonadotropin secretion resulting in loss of normal ovarian function.

Female sex, premenopausal. Central hypogonadism is confirmed as a consequence of hypophysitis. Uterine status is a clinically relevant factor in determining the appropriate treatment formulation.

Management in this population centres on hormone replacement therapy. The specific formulation used differs based on individual anatomical and clinical circumstances.

The complete formulation selection criteria and clinical algorithm are available in the full structured protocol.