Patients with hypertrophic cardiomyopathy who experience angina-like chest pain on exertion in the absence of left ventricular outflow tract obstruction (LVOTO).
Beta-blockers or calcium antagonists (verapamil or diltiazem) represent the initial approach to improving symptoms in this setting. When symptom improvement is not achieved, the protocol escalates to a further treatment option.
An oral agent from a specific drug class may be considered to support symptom improvement in patients without LVOTO. The complete selection criteria, clinical context, and management pathway are available in the full protocol.
DOI: 10.1093/eurheartj/ehad194
Beta-blockers and calcium antagonists (verapamil or diltiazem) should be considered to improve symptoms in patients with angina-like chest pain even in the absence of LVOTO or obstructive CAD.
Oral nitrates may be considered to improve symptoms in patients with angina-like chest pain, even in the absence of obstructive CAD, if there is no LVOTO.
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