Hyperprolactinemia
ICD-10 E22.1 · ICD-11 5A60.1

Treatment of Hyperprolactinemia in Amenorrhea Caused by a Prolactin-Secreting Pituitary Microadenoma

Clinical Scenario

This protocol addresses hyperprolactinemia in female patients presenting with amenorrhea attributable to a prolactin-secreting pituitary microadenoma. The combination of elevated prolactin and menstrual disruption from a microadenoma defines this specific sub-population.

Treatment Approach

Current evidence supports a pharmacological approach targeting the underlying hormonal abnormality. The general strategy involves a choice between two classes of agent — the full treatment selection, criteria, and sequencing are detailed in the complete protocol.

Complete dosing, agent selection criteria, and monitoring parameters are available in the full structured regimen.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1210/jc.2010-1692

We suggest treatment with a dopamine agonist or oral contraceptive in patients with amenorrhea caused by a microadenoma.

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