This protocol addresses hyperprolactinemia in female patients presenting with amenorrhea attributable to a prolactin-secreting pituitary microadenoma. The combination of elevated prolactin and menstrual disruption from a microadenoma defines this specific sub-population.
Current evidence supports a pharmacological approach targeting the underlying hormonal abnormality. The general strategy involves a choice between two classes of agent — the full treatment selection, criteria, and sequencing are detailed in the complete protocol.
DOI: 10.1210/jc.2010-1692
We suggest treatment with a dopamine agonist or oral contraceptive in patients with amenorrhea caused by a microadenoma.
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