Treatment of Overactive Bladder with Urge Incontinence in Huntington's Disease

Urinary incontinence — particularly overactive bladder with urge incontinence and unannounced urination — is a recognised complication in Huntington's disease and requires a structured, stepwise clinical approach.

Clinical scenario: Urinary incontinence in Huntington's disease may be multifactorial or linked to deterioration of frontal lobe control centres, resulting in an overactive bladder with urge incontinence and/or unannounced urination.

Clinical approach: When initial measures prove insufficient, the pathway involves urodynamic evaluation to help determine the appropriate next step — with urological input as needed. The full structured protocol specifies the decision criteria and management sequence.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.3389/fneur.2019.00710

Urinary incontinence may either be multifunctional or linked to a deterioration of the frontal lobe control centers, causing an overactive bladder with urge incontinence and/or unannounced urination.

If simple therapeutic measures have failed, it is advised to undergo urodynamic testing to help guide the choice of drug therapy and to consult a urologist if necessary.

View source ↗