Huntington's disease
ICD-10 G10 · ICD-11 8A01.10

Treatment of Huntington's Disease with Impulsivity Associated with Depression or Personality Disorders

In Huntington's disease, impulsivity — acting without prior planning — can occur alongside depression or personality disorders, creating a specific clinical picture that requires a targeted management approach.

Clinical Scenario

Impulsivity in this context consists of acting without prior planning, which can lead to unpredictable behaviour. When associated with depression or personality disorders, there is an elevated risk of auto- or hetero-aggressiveness, making prompt and appropriate intervention essential.

Treatment Approach (partial overview)

The structured regimen for this scenario involves combining a neuroleptic with an SSRI. Depending on the clinical course, additional long-term pharmacological measures may also be considered — the full protocol details remain ahead.

References

DOI: 10.3389/fneur.2019.00710

Impulsivity consists of acting without prior planning, which can lead to unpredictable behavior.

When impulsivity is associated with depression or personality disorders, there is a risk of auto- or hetero-aggressiveness, which justifies the prescription of a neuroleptic in combination with a SSRI.

Long-term mood-stabilizer treatment may be introduced in the case of mood lability and impulsivity.

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