Huntington's Disease with Hypersalivation and Salivary Incontinence
In Huntington's disease, excessive salivation becomes a distinct clinical problem when it is associated with salivary incontinence — an inability to retain saliva in the mouth resulting from poor oral occlusion and/or faulty swallowing.
Clinical situation: Hypersalivation in Huntington's disease associated with salivary incontinence, arising from poor oral occlusion and/or faulty swallowing mechanics.
Management approach: When oral or oral-mucosa interventions have not provided adequate benefit or have not been tolerated, a targeted injection-based procedure applied to the salivary glands in a specialised setting may be considered. The full protocol details the specific criteria, agent, and clinical context for this step.
References
- Hypersalivation can be troublesome in HD patients when associated with a salivary incontinence (caused by poor oral occlusion and or fault swallowing).
- Injections of botulinum toxin into the salivary glands may be considered in a specialized setting if oral or oral mucosa treatment options have not induced benefit or were not well-tolerated.
DOI: 10.3389/fneur.2019.00710
View source ↗