Huntington's Disease
ICD-10 G10 · ICD-11 8A01.10

Treatment of Huntington's Disease in Depression

This protocol addresses the management of Huntington's disease in a patient who has developed depression — one of the most common psychiatric symptoms encountered in this condition, carrying a significant negative impact on quality of life.

The patient presents with Huntington's disease alongside depressed mood. Identifying and treating this psychiatric comorbidity is a central part of comprehensive HD care.

When depression in Huntington's disease reaches a severe level and proves resistant to oral medications, a specific procedural intervention — administered under specialist psychiatric supervision — may be considered.

Full regimen details, sequencing, and clinical criteria available via the link below →
Instant Access to Structured Evidence-Based Regimens
  1. Depression is one of the most common psychiatric symptoms seen in HD with a significant negative impact on quality of life. DOI: 10.3389/fneur.2019.00710
  2. In case of severe depression and resistant to oral medications, electroconvulsive therapy (ECT) may be suggested under the guidance of a psychiatrist (Grade C). DOI: 10.3389/fneur.2019.00710
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