This protocol addresses Huntington's disease presenting with cognitive impairment — involving deficits in executive function, memory, language, and orientation. Cognitive deficits appear frequently before motor symptoms, making their management a distinct and clinically important consideration.
No pharmacological treatment is recommended for cognitive symptoms in this setting. The structured approach centres on targeted rehabilitation strategies that may help improve or temporarily stabilise cognitive functions at certain stages of the disease course — the complete protocol details which interventions apply and when.
DOI: 10.3389/fneur.2019.00710
Cognitive deficits appear frequently before motor symptoms.
Based on present knowledge, no pharmacological treatment is recommended for the treatment of cognitive symptoms.
Multiple rehabilitation strategies (speech therapy, occupational therapy, cognitive and psychomotricity) might improve or stabilize transitorily cognitive functions at some point of time in the course of the disease (Grade B).
View source ↗