बी वायरस एन्सेफलाइटिस में वायरल एन्सेफलाइटिस का उपचार
बी वायरस संक्रमण के संदर्भ में वायरल एन्सेफलाइटिस एक विशिष्ट और गंभीर नैदानिक परिदृश्य है। केंद्रीय तंत्रिका तंत्र (CNS) की संलिप्तता एक महत्वपूर्ण कारक है जो दवा के चुनाव और उपचार की अवधि को सीधे प्रभावित करती है।
DOI: 10.1086/589747
B virus: valacyclovir is recommended (B-III); alternative agents are ganciclovir (B-III) and acyclovir (C-III).
Valacyclovir (1 g orally every 8 h) is recommended because higher serum concentrations can be achieved.
Some experts recommend ganciclovir (5 mg/kg intravenously every 12 h for a minimum of 14 days or until all CNS symptoms have resolved) if the CNS is involved; subsequent administration of valacyclovir for suppression of latent infection may also be considered.
Acyclovir (12.5–15 mg/kg intravenously every 8 h) has been suggested for acute infection; case reports in patients with B virus encephalitis have demonstrated full recovery, although the efficacy of this approach has not been systematically examined.
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