गंभीर समुदाय-अर्जित निमोनिया में स्यूडोमोनास एरुगिनोसा निमोनिया का उपचार

DOI: 10.1164/rccm.201908-1581ST

The most consistently strong individual risk factors for respiratory infection with MRSA or P. aeruginosa are prior isolation of these organisms, especially from the respiratory tract, and/or recent hospitalization and exposure to parenteral antibiotics.

The major additional risk factors for MRSA and P. aeruginosa identified in the literature are hospitalization and parenteral antibiotic exposure in the last 90 days.

We recommend clinicians only cover empirically for MRSA or P. aeruginosa in adults with CAP if locally validated risk factors for either pathogen are present.

Add coverage for P. aeruginosa and obtain cultures to allow deescalation or confirmation of need for continued therapy.

We believe that the duration of therapy for CAP due to suspected or proven MRSA or P. aeruginosa should be 7 days, in agreement with the recent hospital-acquired pneumonia and ventilator-associated pneumonia guidelines.