प्रणालीगत अंग संलिप्तता के साथ ल्यूकोसाइटोक्लास्टिक वास्कुलिटिस जब प्रेडनिसोन ने रोग निवारण प्राप्त नहीं किया हो

References

DOI: 10.1093/rheumatology/keac115

Conversely, when a systemic vasculitis is the cause of LCV, higher doses of corticosteroids or immunosuppressive agents are required, according to the severity of organ involvement and the underlying associated disease.

When LCV occurs in the context of a systemic vasculitis or an underlying disease, or if none of the above-mentioned agents is effective or tolerated, immunosuppressive medications, such as azathioprine (1–2 mg/kg/day, if thiopurine methyltransferase levels are normal), methotrexate (0.2–0.3 mg/kg/week), with folic acid supplementation, and mycophenolate mofetil (2–3 g/day) can be considered, balancing risks and benefits.