NSAID और कोलचिसीन के प्रति अनुत्तरदायी या असहिष्णु इडियोपैथिक पेरिकार्डिटिस

References

DOI: 10.1161/CIRCULATIONAHA.111.066365

• As a result, and owing to the side effects associated with long-term steroid therapy, glucocorticoids should only be prescribed to patients with idiopathic pericarditis who are refractory to treatment with, or intolerant of, an NSAID plus colchicine.
• A lower dosage (0.25–0.50 mg·kg−1·d−1) for 2 to 4 weeks, followed by slow tapering is effective and is associated with fewer relapses than the higher dosage.
• With prolonged corticosteroid use, osteoporosis prevention (eg, calcium, vitamin D, and bisphosphonates) should be considered.
• Steroid therapy has long been used to treat pericarditis because it induces prompt symptomatic relief; however, glucocorticoids should not be used as primary therapy in uncomplicated acute idiopathic pericarditis because of a high rate of relapse when the steroid is tapered or stopped.