इडियोपैथिक पेरिकार्डिटिस का उपचार क्या है? प्रथम-पंक्ति साक्ष्य-आधारित दृष्टिकोण

References

DOI: 10.1161/CIRCULATIONAHA.111.066365

• It is now common practice to include colchicine, in combination with an NSAID, as initial management of acute idiopathic pericarditis.
• Aspirin and other NSAIDs are the first-line approach, based on clinical experience and observational reports.
• Concurrently, rest and avoidance of demanding physical activity help to minimize symptoms.
• Because high doses are often required, consideration should also be given to gastric protection therapy (eg, a proton pump inhibitor or misoprostol).
• Appropriate therapy for acute idiopathic pericarditis is an NSAID for ≈2 weeks, and it is also reasonable to prescribe colchicine for up to 3 months, especially to reduce the rate of recurrence.
• Commonly used NSAID regimens are listed in the Table, with a recommended initial duration of 7 to 14 days, then treatment should be tapered until resolution of symptoms and improvement of acutely elevated serum inflammatory markers such as C-reactive protein and the erythrocyte sedimentation rate.