गंभीर इम्यूनोकॉम्प्रोमाइज़्ड रोगियों में दवा-प्रतिरोधी या चिकित्सीय रूप से दुर्दम्य जननांग हर्पीस का उपचार

References

DOI: 10.1111/jdv.20450

Although rare in immunocompetent individuals, clinically refractory lesions due to genital HSV are a major problem in patients with severe immunodeficiency, including late-stage HIV.

Systemic therapy with either foscarnet or cidofovir is generally preferred to treat drug-resistant herpes in those living with HIV.

There is evidence for alternating courses of treatment with aciclovir and cidofovir for subsequent recurrences as a strategy that may reduce the development of cidofovir-resistant strains.