नींद के दौरान सतत स्पाइक-एंड-वेव के साथ एपिलेप्टिक एन्सेफैलोपैथी का उपचार क्या है?

References

DOI: 10.1016/j.jpeds.2021.01.032

• There are currently four primary treatment strategies: high-dose oral benzodiazepines given before sleep, steroids, other anti-seizure medications (ASMs), or epilepsy surgery.
• CSWS treatments were categorized as: (a) benzodiazepines (clobazam and oral diazepam), (b) steroids; (c) ASMs; and (d) other (including surgery, ketogenic diet, IVIG).
• While the majority of patients first receive a benzodiazepine, a sizeable minority receive one of several ASMs and very few first receive steroids.
• The clinical response was defined as clinical improvement in neurocognitive function, seizures, or the EEG after therapy as judged and documented in the medical record by the treating neurologist.
• The SWI response was defined by a 50% reduction in the sleep SWI when comparing the post- and pre-treatment EEGs.