एम्फिसेमेटस पायलोनेफ्राइटिस का प्रारंभिक उपचार क्या है?

References

DOI: 10.1038/nrurol.2009.51

• The initial management of a patient with EPN is resuscitation; a three-pronged approach should be put into place to address fluid/hemodynamic status, diabetic control and an antibiotic regimen.
• Patients who are moribund at presentation might need ventilatory support.
• Treatment of patients with EPN comprises resuscitation, correction of any electrolyte and glucose problems, and administration of antibiotics targeting Gram-negative bacteria.
• The choice of antibiotic regimen should be appropriate for targeting Gram-negative bacteria, and will be determined by the local hospital policy (and any knowledge of the sensitivity of the organism involved in the infection), but usually includes aminoglycosides, β-lactamase inhibitors, cephalosporins and quinolones.
• Park and colleagues use piperacillin and tazobactam empirically.
• Shokeir et al. and Chan et al. used a cephalosporin together with an aminoglycoside.