अंतर्निहित सिरोसिस के बिना हाल की PVT में तीव्र पोर्टल शिरा घनास्त्रता का उपचार

References

DOI: 10.1016/j.jhep.2025.08.001

• Anticoagulation initiated as soon as possible is the first-line therapy for recent PVT in the absence of cirrhosis.
• Anticoagulation should be initiated as soon as possible, since early initiation of anticoagulation may reduce the risk of developing intestinal ischaemia and increases the probability of portal vein recanalisation.
• Anticoagulation should be continued for at least 6 months.
• Anticoagulation initiated as soon as possible is the treatment of choice.
• In patients with recent PVT without cirrhosis, direct oral anticoagulants are suggested as an alternative to low-molecular-weight heparin and/or vitamin K antagonists, during the first 6 months after PVT diagnosis, to reduce morbidity and mortality.
• In patients with recent PVT, there are two main goals of anticoagulant treatment: (i) to prevent bowel necrosis requiring bowel resection and (ii) to achieve sufficient recanalisation of the portal venous system to prevent the future development of portal hypertension and its complications.