Treatment of Herpes Simplex Keratitis in HSV Epithelial Keratitis
HSV epithelial keratitis is a specific clinical presentation of herpes simplex keratitis in which the corneal epithelium is involved. Effective management in this setting follows a distinct approach that differs from other forms of ocular herpes infection.
Clinical scenario: This protocol addresses patients with HSV epithelial keratitis. In this presentation, antiviral agents alone are the established treatment of choice.
Treatment approach (partial overview): Management is centred on antiviral agents, with both topical and oral options available. An important management consideration is that topical corticosteroids should be avoided during initial treatment. In situations where antiviral agents cannot be used, a mechanical alternative may be considered. Full agent selection, sequencing, and clinical criteria are available in the complete protocol below.
References
- Antiviral agents alone are the treatment of choice for HSV epithelial keratitis.
- Topical corticosteroids should be avoided in the initial management of HSV epithelial keratitis.
- There are two topical and three systemic antiviral agents available and actively used for the treatment of HSV epithelial keratitis in the United States.
- When antiviral agents are contraindicated or unavailable, debridement may be used as an alternative treatment.
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