Treatment of Hereditary Hemochromatosis in Decompensated Liver Disease and Advanced Hepatic Cirrhosis

This protocol applies to patients with hereditary hemochromatosis who have progressed to advanced hepatic cirrhosis with decompensated liver disease — a stage at which standard iron-depletion management is no longer sufficient.

Advanced cirrhosis in hereditary hemochromatosis is not reversed with iron removal. Once decompensated liver disease develops, the clinical picture changes substantially and a different treatment pathway must be considered.

In this setting, the treatment approach centres on a major surgical intervention targeting the liver itself. The full structured protocol defines the specific indication criteria, patient selection considerations, and the complete management pathway.

The complete regimen and decision criteria are available via the protocol link below.