This protocol covers management of hepatocellular carcinoma (HCC) in patients with well-compensated liver cirrhosis (Child-Turcotte-Pugh class A), where the hepatic reserve and tumor characteristics meet specific surgical eligibility thresholds.

Clinical scenario

Liver cirrhosis, Child-Turcotte-Pugh class A (well compensated)
Limited hepatic tumor burden
Absence of clinically significant portal hypertension
Adequate future liver remnant

Treatment approach — partial overview

For eligible patients in this setting, a transplant-based surgical option may be appropriate under specific defined criteria. The complete protocol specifies the conditions, eligibility thresholds, and decision pathway in full.

References

DOI: 10.1097/HEP.0000000000000466

In patients with cirrhosis, surgical resection should be considered the treatment of choice for patients with limited tumor burden, well-compensated cirrhosis without clinically significant portal hypertension, and an adequate FLR (Level 2, Strong Recommendation).

Liver transplantation should be the treatment of choice for transplant-eligible patients with HCC that recur within Milan criteria after surgical resection (Level 3, Strong Recommendation).

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Treatment of Hepatocellular Carcinoma in Well-Compensated Liver Cirrhosis (Child-Turcotte-Pugh Class A)

References