Treatment of Henoch-Schönlein Purpura in Recurrent Purpuric Skin Rash

Clinical Scenario

This protocol addresses Henoch-Schönlein purpura in patients experiencing a recurrent purpuric skin rash. Recurrence of the characteristic purpuric lesions represents a distinct clinical challenge that calls for a structured, stepwise treatment approach.

Treatment Approach

In recurrent cases, an initial pharmacological therapy is applied first. For patients who do not respond adequately, immunosuppressive agents form the next step in the sequence. The specific agents, their order, and the criteria for escalation are defined in the full protocol.

Agent selection, sequencing, and escalation criteria are detailed in the complete regimen below.