Treatment of Henoch-Schönlein Purpura with Cerebral Vasculitis
Henoch-Schönlein purpura (HSP) occasionally presents alongside or complicated by cerebral vasculitis, a neurological involvement that substantially shapes the clinical approach. This page outlines the key considerations and points to the full structured treatment protocol.
In HSP with concurrent cerebral vasculitis, the clinical picture must be carefully evaluated against other possible causes — including hemorrhage, infarcts, and infections — before any treatment is initiated.
For severe, recurrent, or resistant presentations, the protocol involves an alkylating immunosuppressive agent. The complete selection criteria, sequencing, and regimen details are available in the full protocol below.
- Cerebral vasculitis should be investigated according to the presenting manifestations to exclude other possible causes including hemorrhage, infarcts, and infections before starting treatment.
- Cyclophosphamide can be considered in severe, recurrent or resistant case.