Hand-foot-and-mouth disease
ICD-10 B08.4 · ICD-11 1F05.0

Treatment of Uncomplicated Hand, Foot and Mouth Disease or Herpangina with Oral Ulcers

This protocol covers the management of uncomplicated HFMD or herpangina: a febrile illness presenting with a papulovesicular rash on the palms and soles and/or ulcers in the mouth, with mucocutaneous involvement only and no warning signs of central nervous system involvement.

Clinical Scenario
Febrile illness with papulovesicular rash on palms and soles, with or without vesicles or ulcers in the mouth, and no CNS warning signs. Children with mucocutaneous involvement only may be managed at home, provided there are no social circumstances of concern such as anxious parents or poor access to health care facilities.
Management Approach
In the majority of cases, HFMD is a self-limiting illness. Management is symptomatic and supportive in nature — the full protocol details the specific recommended measures for symptom relief and hydration. There are no specific antivirals.
Instant Access to Structured Evidence-Based Regimens

References

Children with mucocutaneous involvement only (i.e. uncomplicated HFMD) may be treated at home, as long as there are no social circumstances of concern, such as anxious parents or poor access to health care facilities.

HFMD Febrile illness with papulovesicular rash on palms and soles, with or without vesicles/ulcers in the mouth.

In most cases, HFMD is a self-limiting illness, with the majority of children recovering spontaneously with symptomatic treatment.

Clinical management of HFMD is largely supportive in nature and there are no specific antivirals.

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