Treatment of Granuloma Inguinale in a Newborn Born to a Mother with Donovanosis

Newborns delivered to a mother with donovanosis represent a distinct clinical scenario. Guidelines address this population directly, recommending active prophylactic management at the time of birth rather than a watch-and-wait approach.

The infant is born to a mother with donovanosis (granuloma inguinale). This maternal infection history places the neonate in a defined risk category for which a specific, evidence-graded prophylactic protocol exists.

Prophylaxis with azithromycin is recommended for these newborns. The complete regimen — including the dosing schedule and duration — is set out in the full structured protocol.