Gonorrhoea does not always remain localised. When Neisseria gonorrhoeae spreads via transluminal extension from the urethra or endocervix, it can involve the upper reproductive tract, producing gonococcal pelvic inflammatory disease — a distinct clinical situation that calls for a targeted treatment approach.
Pelvic inflammatory disease (PID) is a recognised complication of gonorrhoea. Upward spread of N. gonorrhoeae from the lower genital tract can result in upper reproductive tract infection, requiring management that addresses both the gonococcal aetiology and the PID syndrome together.
Management in this scenario involves an antibiotic component added to the PID treatment regimen — used alongside whichever regimen is selected for the pelvic inflammatory disease itself. The two components are given concurrently to address the full clinical picture.
Transluminal spread of N. gonorrhoeae from the urethra or endocervix may occur and cause epididymo-orchitis, prostatitis or pelvic inflammatory disease (PID).
Ceftriaxone 1 g IM as a single dose in addition to the regimen chosen to treat PID.
DOI: 10.1177/09564624251345195
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