Giant cell tumor of bone
ICD-10 D48.0ICD-11 2F9B

Treatment of Giant Cell Tumor of Bone in Multicentric Disease with Multiple Lesions

Multicentric giant cell tumor of bone (GCTB) is a distinct clinical scenario in which multiple bone lesions occur simultaneously or asynchronously. It predominantly affects young patients and presents unique management challenges compared with solitary GCTB.

This protocol applies to patients with multicentric giant cell tumor of bone — defined by the presence of multiple lesions. The condition typically occurs in young individuals and may present with a pattern of asynchronous tumour development across affected sites.

Surgical intervention at the lesion sites is a central component of management in this setting.

The complete structured protocol — including the full sequence of interventions, site-specific considerations, and decision criteria — is available via the link below.

References
DOI: 10.3390/curroncol31040157
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