Pulmonary metastasis is an uncommon but recognised complication of giant cell tumor of bone. Determining the appropriate first step in management for this presentation requires a structured, evidence-based approach.
For this presentation, initial management may take a more conservative direction than might be expected — the full structured protocol outlines the specific approach, the criteria that guide it, and when escalation becomes appropriate.
DOI: 10.3390/curroncol31040157
Pulmonary metastasis occurs in 1–9% of cases.
Hence, observation is recommended for initial management.
Of those who developed pulmonary metastases, 45% (10/22) were initially managed through observation; in these patients, the disease remained stable.
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