This protocol covers pemphigoid gestationis that remains active following delivery or pregnancy loss — a presentation that occurs outside of pregnancy itself, in the post-partum or post-abortion period, and that calls for a specific therapeutic strategy distinct from in-pregnancy management.
First-line management in this period centres on immunosuppressant or immunomodulating therapy. One agent used in this setting requires specific infant monitoring when the mother is breastfeeding.
DOI: 10.3389/fmed.2020.604945
In the post-partum/post-abortion period, we suggest as first step treatment immunosuppressant/immunomodulating agents, including dapsone and azathioprine, leaving as second choices IVIg and rituximab due to pharmacoeconomic reasons.
Dapsone (during lactation monitor infant G6PDH deficiency and hemolysis)
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