Treatment of First-Episode Genital Herpes Acquired During Pregnancy

Clinical Scenario

This protocol covers women who acquire a primary episode of genital herpes during pregnancy — a situation requiring careful clinical assessment, with particular attention to the trimester in which acquisition occurs.

Pregnancy — Key Consideration

Because this is a first-episode infection occurring in a pregnant patient, management must be tailored to both the woman's clinical condition and the gestational timing. First- and second-trimester acquisitions follow a defined clinical pathway that differs from episodes acquired later in pregnancy.

Treatment Approach (Overview)

Antiviral therapy forms the basis of management, with the route of treatment selected according to the woman's clinical status. Complete regimen details, route selection criteria, and the full clinical decision pathway are available in the structured protocol below.

Instant Access to Structured Evidence-Based Regimens

References

DOI: 10.1111/jdv.20450

Management of the woman should be in line with her clinical condition and will often involve the use of either oral or intravenous aciclovir in standard doses (Figure 4).

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